ABEYWARDANE ASITHA,BURKE MICHAEL J.,KIRRANE THOMAS MARTIN JR.,NETHERTON MATTHEW RUSSELL,PADYANA ANIL KUMAR,SMITH KEENAN LANA LOUISE,TAKAHASHI HIDENORI,TURNER MICHAEL ROBERT,ZHANG QIANG,ZHANG QING
申请号：
NZ61410912
公开号：
NZ614109A
申请日:
2012.03.13
申请国别(地区):
NZ
年份:
2015
代理人:
摘要：
Disclosed are benzodioxane compounds and their pyridodioxinyl derivatives of formula (I) wherein the variables are as defined in the specification. The compounds of formula (I) are useful as inhibitors of leukotriene A hydrolase (LTA4H) enzyme and treating LTA4H related disorders such as asthma, allergy and cardiovascular diseases including atherosclerosis, myocardial infarction and stroke. Also disclosed are processes for preparing compounds of formula (I), pharmaceutical compositions comprising the compounds of formula (I), and methods of using these compounds in the treatment of said diseases and disorders.
