ANDERSKEWITZ, RALF,MARTYRES, DOMNIC,OOST, THORSTEN,RIST, WOLFGANG,SEITHER, PETER
申请号:
CA2825458
公开号:
CA2825458A1
申请日:
2012.01.20
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present invention relates to pyrazole compounds of formula (1a) or (1b) and pharmaceutically acceptable salts thereof, wherein Ra, Rb, Rc, Rd, Y1, y2, y3, y4, y5, Z, R1, R2, n and R3 have one of the meanings as indicated in the specification and claims, to their use as medicaments, to pharmaceutical formulation containing said compounds and to pharmaceutical formulations said compounds in combination with one or more active substances. The compounds have CRTH2 antagonistic activity.