Jessica J. O'Konek;Masaki Terabe;Petr Illarionov;Jay A. Berzofsky;Gurdyal S. Besra
发明人:
Jay A. Berzofsky,Jessica J. O'Konek,Masaki Terabe,Petr Illarionov,Gurdyal S. Besra,Jessica J. OKonek
申请号：
US13582612
公开号：
US08835613B2
申请日:
2011.03.11
申请国别(地区):
US
年份:
2014
代理人:
摘要：
β-mannosylceramides or salts or solvates thereof in a pharmaceutically acceptable carrier, for use as a Type I NKT cell agonist in conjunction with a therapeutically effective amount of α-galactosylceramide or a salt or a solvate thereof, and/or at least one or more T-cell co-stimulatory molecules, disclosed. Compositions comprising β-mannosylceramide, as well as methods of treatment of tumors are also provided.
