Polyurethane, including insulin-1 growth factor (IGF-1), in which amino acids at position 42 are inhibited or mutated； polyribose； pharmaceutical ingredients containing the factor； and drugs for the production of muscle disorders.

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专利权人:

NOVARTIS AG

发明人:

FORNARO MARA,HUBER THOMAS,ZURINI MAURO

申请号：

CL2015001708

公开号：

CL2015001708A1

申请日:

2015.06.17

申请国别(地区):

CL

年份:

2015

代理人:

摘要：

This invention is in the field of IGF-1 modifications. In particular, it relates to modified IGF-polypeptides and modified IGF-1 precursor polypeptides wherein the cleavage of E-peptide is prevented. The invention also relates to the use of such polypeptides for treating muscle diseases and disorders.POLIPÉPTIDO QUE COMPRENDE EL FACTOR DE CRECIMIENTO TIPO INSULINA 1 (IGF-1), DONDE EL AMINOÁCIDO GLICINA EN POSICIÓN 42 ES SUPRIMIDO O CON LA SUSTITUCIÓN G42S； COMPOSICIÓN FARMACÉUTICA QUE LO COMPRENDE； Y USO PARA PREPARAR UN MEDICAMENTO PARA TRATAR UN TRASTORNO MUSCULAR

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中国工程科技知识中心

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http://www.ckcest.cn/home/