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Blood processing apparatus with robust automated process control
专利权人:
发明人:
Christopher Fletcher,William Sweat,Jeremy P. Kolenbrander,Aditya Dalvi,John R. Lindner
申请号:
US13679034
公开号:
US08449439B2
申请日:
2012.11.16
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A centrifuge for separating blood having a camera observing fluid flow, and a controller controlling the flow. The location of an interface is detected by image processing steps, which may comprise the steps of “spoiling” the image, “diffusing” the image, “edge detection”, “edge linking”, “region-based confirmation”, and “interface calculation”. “Spoiling” reduces the number of pixels to be examined preferentially on orthogonal axis oriented with respect to the expected location of the interface or phase boundary. “Diffusing” smoothes out small oscillations in the interface boundary, making to the location of the interface more distinct. “Edge detection” computes the rate of change in pixel intensity. “Edge linking” connects adjacent maxima. “Region-based confirmation” creates a pseudo image of the regions that qualify as distinct. “Final edge calculation” uses the points where the shade changes in the pseudo image, averages the radial displacement of these points for the interface position.
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