ナノ粒子支持体表面にコーティングされたT1造影物質を含むMRI造影剤

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专利权人:

インダストリー-アカデミック コーポレーション ファウンデーション,ヨンセイ ユニバーシティ

发明人:

チョン・ジヌ,シン・テヒョン

申请号：

JP2015551605

公开号：

JP6309542B2

申请日:

2014.01.03

申请国别(地区):

JP

年份:

2018

代理人:

摘要：

The present invention relates to a magnetic resonance imaging (MRI) T1 contrast agent composition including T1 contrast material coated on the surface of a nanoparticle support. The MRI T1 contrast agent composition of the present invention has excellent T1 spin magnetic relaxation effects by modifying the paramagnetic T1 contrast material on the nanoparticle support having a certain diameter such that the paramagnetic T1 contrast material has a certain thickness or less, and thereby remarkably increasing the surface-to-volume ratio of the T1 contrast material. The present invention provides more precise and clear T1 positive contrast images, and is thus useful for highly reliable image diagnosis.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/