Michael Fontaine,Ruth Nicolet Zadoks,Christian Marie Joseph Delannoy
申请号：
US15508327
公开号：
US10786560B1
申请日:
2015.09.03
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present disclosure is based upon the identification of a number of Streptococcus agalactiae genes which are required for virulence in fish species. Specifically, the disclosure relates to genomic content present in fish-associated S. agalactiae strains that is absent from strains which are non-virulent to fish. Further disclosed is the use of a number of S. agalactiae proteins and antigens in methods, immunogenic compositions and vaccines for raising immune responses and treating or preventing diseases, conditions and/or infections with a Streptococcal aetiology.
