MARZENA MAZUR,ROBERT KORALEWSKI,BARTLOMIEJ BOREK,SYLWIA OLEJNICZAK,WOJCIECH J. CZESTKOWSKI,MICHAL C. PIOTROWICZ,JACEK P. OLCZAK,ADAM A. GOLEBIOWSKI,AGNIESZKA BARTOSZEWICZ,ELZBIETA PLUTA,MICHAL L. KOWA
申请号:
PT16767368
公开号:
PT3344616T
申请日:
2016.09.02
申请国别(地区):
PT
年份:
2019
代理人:
摘要:
Disclosed are amino triazole compounds substituted with a piperidinyl ring that is itself substituted with a heterocyclic ring. These compounds are inhibitors of acidic mammalian chitinase and chitotriosidase. Also disclosed are methods of using the compounds to treat asthma reactions caused by allergens, as well as acute and chronic inflammatory diseases, autoimmune diseases, dental diseases, neurologic diseases, metabolic diseases, liver diseases, polycystic ovary syndrome, endometriosis, and cancer.