The invention relates to the field of pharmacy, clinical and experimental medicine and veterinary medicine, and in particular to novel inhibitory compounds of a p38 MAP kinase with a structure of the type (I)-(VII) which can be used for the treatment or prophylaxis of adhesion. The invention discloses pharmaceutical compositions containing an effective amount of the substance SB203580 or one of the compounds of the type (I)-(VII) or a combination thereof and a pharmaceutically acceptable carrier, a diluent or an excipient. Also disclosed is the use of the substance SB203580 as an agent having anti-adhesion activity. Also disclosed is: a method for the prophylaxis and/or treatment of a disease or a condition in which there is the possibility of the formation and/or growth of adhesions which makes it possible to dispense with the additional administration of a preparation in the post-operative period.
