Food for the prevention or treatment of diabetic retinopathy and food for the prevention or treatment of diabetic retinopathy, food for improving various signs of diabetic retinopathy, food for the purpose of improving various signs of diabetic retinopathy, and diabetic retinopathy Method for determining the timing of administration of a preventive or ameliorating agent
The present invention relates to a preventive or therapeutic agent for diabetic retinopathy characterized by containing lutein, the prophylactic or therapeutic agent for administration at an early stage of diabetic retinopathy including simple retinopathy or preproliferative retinopathy, Electroretinogram-improving agent, retinal ganglion cell apoptosis inhibitor, neurotransmission-related molecule decrease inhibitor, ERK activation inhibitor, brain-derived neurotrophic factor decrease inhibitor, electroretinogram measurement values are normal Prevention or amelioration of diabetic retinopathy by comparing with electroretinogram measurements of the retinal or by observing changes in the thickness of the inner retinal layer, inner granule layer, and ganglion cell layer of the retina by optical coherence tomography This is a method for determining the timing of administration of a drug.本発明は、ルテインを含むことを特徴とする、糖尿病網膜症の予防又は治療剤，単純網膜症又は前増殖網膜症を含む糖尿病網膜症の初期段階において投与するための、当該予防又は治療剤，網膜電図の改善剤，網膜神経節細胞のアポトーシス抑制剤，神経伝達関連分子の減少抑制剤，ERK活性化抑制剤，脳由来神経栄養因子の減少抑制剤，網膜電図の測定値を正常時の網膜電図の測定値と比較することによって、或いは網膜の内網状層、内顆粒層、神経節細胞層の厚みの変化を光干渉断層法で観察することによって、糖尿病網膜症の予防又は改善剤の投与時期を決定する方法である。
