FIELD: chemistry.SUBSTANCE: invention relates to a compound of formula (I) or pharmaceutically acceptable salts thereof [Chemical formula 1],where [Chemical formula 2]is , orY1 and Y2, each independently represent N(RY) or O； Z1 is C(R4) or N； Z2a is C(R5a) or N； Z2b is C(R5a) (R5a') or N(R5b)； Z2c is C(R5a) or N； Z3a is C(R6) or N； provided that when Z1 is N, then each of Z2a, Z2b and Z2c is C(R5a)； when Z1 is C(R4), then Z2c is N； and when Z2a is N, then Z3a is C(R6)； RY, each independently represents a hydrogen atom, hydroxy, cyano, unsubstituted alkyl, unsubstituted alkyloxy； R4 and R6, each independently represent a hydrogen atom, halogen, substituted or unsubstituted alkyl, where substitutes are selected from alkyloxy； R5a and R5a', each independently represent a hydrogen atom, halogen, carboxy, carbamoyl, cyano, substituted or unsubstituted alkyl, where substitutes are selected from alkyloxy and hydroxy, unsubstituted alkyloxy； R5b is unsubstituted alkyl； R1 is phenyl substituted with one or more halogen atoms and optionally substituted with one or more identical or different substitutes selected from alkyl, haloalkyl, alkyloxy； R2a, each independently represents a hydrogen atom； R2b, each independently represents a hydrogen atom； X is N(R7a)； R7a is a hydrogen atom； R2c, each independently represents a hydrogen atom； R2d, each independently represents a hydrogen atom； R3 represents a group represented by formula [Chemical formula 3], ,where Ring B is benzene or pyridine； Ring C is cyclopentane； n is equal to 1； m is integer from 0 to 1； p1 is integer from 0 to 2； p2 is equal to 1 (values of other radicals are presented in claim 1).EFFECT: compounds have P2X7 receptor antagonist activity.24 cl, 250 tbl, 36 exИзобретение относится к соединению формулы (I) или его фармацевтически приемлемым солям[Химическая формула 1]где[Химическая формула 2]представляет собойY1 и Y2, каждый независимо, представляют собой N(RY) или O； Z1 представляет собой C(R4) или N； Z2a пре
