COMPOSITION PHARMACEUTIQUE STABLE

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专利权人:

Astellas Pharma Inc.

发明人:

申请号：

EP17864986.9

公开号：

EP3533448A1

申请日:

2017.10.25

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

Provided is a pharmaceutical composition, which comprises 5-{[(3R)-1-acryloylpyrrolidin-3-yl]oxy}-6-ethyl-3-({4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}amino)-pyrazine-2-carboxamide or a pharmaceutically acceptable salt thereof, and is stabilized. The pharmaceutical composition comprises potassium chloride and/or sodium chloride, and inhibits the increase of related substances.

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