VACCIN A BASE DE POLYSACCHARIDE DESTINE A COMBATTRE LES INFECTIONS AUX STAPHYLOCOQUES

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专利权人:

THE BRIGHAM AND WOMEN'S HOSPITAL; INC.

发明人:

PIER, GERALD B.,MAIRA-LITRAN, TOMAS

申请号：

CA2501077

公开号：

CA2501077C

申请日:

2003.11.12

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

The invention relates to compositions of a deacetylated poly N-acetylatedglucosamine (dPNAG) of Staphylococci. The dPNAG may be isolated from naturalsources or synthesized de novo.The invention also relates to the use of dPNAGas a vaccine for inducing active immunity to infections caused byStaphylococcus aureus, S. epidermidis, other related coagulase-negative orcoagulase-positive Staphylococci, and other organisms carrying the ica(intracellular adhesion) locus. The invention further provides methods of usefor antibodies directed to dPNAG, particularly for inducing passive immunityto the same class of infections.

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中国工程科技知识中心

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