ANDRIEN, Bruce, A.,SHERIDAN, Douglas, L.,TAMBURINI, Paul, P.
申请号：
HK16105197.2
公开号：
HK1217207A
申请日:
2016.05.06
申请国别(地区):
HK
年份:
2016
代理人:
摘要：
The disclosure provides antibodies that are useful for, among other things, inhibiting terminal complement (e.g., the assembly and/or activity of the C5b-9 TCC) and C5a anaphylatoxin-mediated inflammation and, thus, treating complement-associated disorders. The antibodies have a number of improved properties relative to eculizumab, including, e.g., increased serum half-life in a human.
