The invention relates to a filling and closing device (20) for an applicatorforactive substances (1) and to a method for filling and closing such anapplicator for activesubstances (1) by means of such a filling and closing device (20). Theapplicator foractive substances (1) comprises an applicator tube (7) that overlaps thesealing edge (5),at least in part. The filling and closing device (20) comprises a receivingelement (21) forthe lower part (2) of the applicator for active substances (1), having acircumferentialpressure surface (22) and a receiving channel (23) for the applicator tube(7), saidreceiving channel extending below the pressure surface (22). The receivingelement (21)is constructed of at least two parts, having a base element (24) and a coverelement (25)that is movable with respect to the base element (24). After completion of thefilling andsealing process, the cover element (25) is moved relative to the base element(24), suchthat the receiving channel (23) formed therebetween is exposed. The filled andsealedapplicator for active substances (1) can then be easily removed from thereceivingelement (21) by way of the applicator tube (7).