Method for the preparation of at least one compound with biologicalproperties from blood, where said method is performed in sealed tubes at apressure below atmospheric pressure, thereby reducing or preventing thebacterial contamination of the compound through handling. The methodcomprises the repetition, for as many times as is required, of the followingsteps: connecting a second container that is vacuum-sealed to an extractiondevice connected in turn to a first container that contains blood separatedintofractions, waiting for a period of time until the required fraction (s) is/aretransferred, and removing said second container, with it thus being possibletoobtain several second containers with different compounds for differentmedical applications including biological therapies. The steps may beperformed in a closed system, without removing the caps of the containers, oralternatively the first container may be opened prior to the introduction oftheextraction device.
