The present invention relates to water soluble caffeine, a manufacturing method thereof, and a processed product comprising the water soluble caffeine as a main material. More particularly, the water soluble caffeine has improved thermal stability and skin permeability at low temperatures, and increases the amount of caffeine dissolved in water by using a principle of molecular complexes between caffeine and a cyclic low-molecular substance having a molecular structure similar to a water soluble low-molecular substance and caffeine. The water soluble low-molecular substance and the cyclic low-molecular substance form a physical bonding with caffeine, and the physical bonding may be one of pi-pi stacking, a hydrophobic interaction, and all physical bonds formed between molecules.COPYRIGHT KIPO 2016본 발명은, 수용성 저분자 물질 및 카페인과 분자구조가 유사한 고리형 저분자 물질과 카페인 간의 분자복합체 원리를 이용하여, 물에 용해되는 카페인 함량을 증가시키고, 저온에서의 온도 안정성 및 피부투과성을 향상시킨 수용성 카페인, 그 제조방법 및 이 수용성 카페인을 주원료로 하는 가공제품을 제공한다.