New Stable Formulations of Recombinant Human Albumin-Human Granulocyte Colony Stimulating Factor Fusion Protein

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专利权人:

Teva Pharmaceutical Industries Ltd.

发明人:

Bock, Jason Benjamin,Luo, Xia

申请号：

AU2014202190

公开号：

AU2014202190B2

申请日:

2014.04.22

申请国别(地区):

AU

年份:

2016

代理人:

摘要：

#$%^&*AU2014202190B220160317.pdf#####ABSTRACT Described herein are compositions and methods for treating, preventing and ameliorating diseases and conditions characterized by a lower than normal white blood cell count, such as leukopenia and neutropenia. The compositions and methods include recombinant human albumin-human granulocyte colony stimulating factor. Pharmaceutical formulations including the recombinant fusion protein, and methods of making such formulations are also described.1/39 FIGURE 1 Effects of Concentrations on rHSA-G-CSF 105 100, 95: 3 85 08 75 0 50 100 150 200 250 Concentration (mglml)

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