COMPER, WAYNE,RAMACHANDRAN, APARNA,YAN, HAOHENG,RUSSO, LEILEATA, M.,SKOG, JOHAN KARL OLOV
申请号：
EP13844278
公开号：
EP2903597A4
申请日:
2013.10.03
申请国别(地区):
EP
年份:
2016
代理人:
摘要：
The present invention discloses methods for diagnosing or prognosing a disease or medical condition in a subject by detecting the presence or absence of BRAF mutant nucleic acids from nucleic acids extracted from microvesicles from a biological sample. The present invention also discloses methods for assessing the responsiveness or determining a treatment regimen for a subject in need thereof by detecting the presence or absence of BRAF mutant nucleic acids from nucleic acids extracted from microvesicles from a biological sample. Methods for isolating microvesicles and extracting DNA and/or RNA from the microvesicles are also described.
