7-[3,5-DIHYDROXY-2- (3-HYDROXY-5-PHENYL-PENT-1-ENYL)- CYCLOPENTYL]-N-ETHYL-HEPT-5-ENAMIDE (BIMATOPROST) IN CRYSTALLINE FORM II, METHODS FOR PREPARATION, AND METHODS FOR USE THEREOF

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专利权人:

ALLERGAN; INC.

发明人:

AMBRUS, GYORGY, F.,KARAMI, KIOMARS,WU, KE

申请号：

SG2012037842

公开号：

SG181015A1

申请日:

2010.11.19

申请国别(地区):

SG

年份:

2012

代理人:

摘要：

The present invention provides a new crystalline form of bimatoprost, designated as crystalline form II. This new crystalline form is the most stable form known to date of bimatoprost. Moreover, it has been found that bimatoprost crystalline form II is readily prepared from crystalline form I.

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