Apparatus, method and computer accessible medium can be provided for determining presence of individual scattering objects in at least one blood vessel. For example, with at least one detector arrangement, it is possible to detect interferometric radiation from at least one portion of the blood vessel(s), and provide data associated therewith. The interferometric radiation can be based on a first radiation provided from the portion at a second radiation provided from a reference. Further, with a computer arrangement, it is possible to determine the presence of the individual scattering objects in the portion of the blood vessel(s) based on the data. It is also possible to identify individual passage of the scattering objects and/or measure at least one characteristic of the passage.
