An elbow prosthesis according to the present teachings can include a stem structure and an articulating component. The stem structure can be operable to be positioned in a bone of a joint. The stem structure can include a stem portion that is operable to be positioned in the bone and a C-shaped body portion having a first retaining mechanism formed thereon. The articulating component can have a second retaining mechanism formed thereon. One of the first and second retaining mechanisms can include an extension portion and a first anti-rotation portion. The other retaining mechanism can include a receiving portion and a second anti-rotation portion. The articulating component can be advanced from an insertion position to an assembled position, such that the first and second mechanisms cooperatively interlock to inhibit translation and rotation of the articulating component relative to the C-shaped body portion of the stem structure.