SYNTHESIS OF RALTEGRAVIR
- 专利权人:
- 发明人:
- 申请号：
- EP12862643.9
- 公开号：
- EP2804607A2
- 申请日:
- 2012.12.21
- 申请国别(地区):
- EP
- 年份:
- 2014
- 代理人:
- 摘要：
- The present invention relates to a novel synthetic route for the preparation of raltegravir and pharmaceutically acceptable salts, starting from 2-amino-2-methylpropanenitrile and oxadiazole carbonyl chloride, through the formation of a pyrimidinone intermediate of formula (V).
- 来源网站：
- 中国工程科技知识中心
