Scott Edward MOSELEY,Andrew E. DENKER,Wei-Jian PAN
申请号：
US16498143
公开号：
US20200101141A1
申请日:
2018.03.29
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The disclosure features methods for treating hypophosphatasia (HPP) in a patient (e.g., an adult having HPP, such as an adult having pediatric-onset HPP, or an adolescent having HPP) exhibiting decreased pyrophosphate (PPi) or pyridoxal 5′；-phosphate (PLP) concentrations in, e.g., a plasma sample, physical impairments, or decreased walking ability by administering a soluble alkaline phosphatase (sALP) to the patient.
