SPOSOBY I KOMPOZYCJE DO DOSTARCZANIA SULFATAZY-2-IDURONIANIU DO OUN

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专利权人:

Inc.;Shire Human Genetic Therapies

发明人:

ZHU, GAOZHONG,LOWE, KRIS,SHAHROKH, ZAHRA,CHRISTIAN, JAMES,FAHRNER, RICK,PAN, JING,WRIGHT, TERESA LEAH,CALIAS, PERICLES

申请号：

PL11799036

公开号：

PL2593131T3

申请日:

2011.06.25

申请国别(地区):

PL

年份:

2020

代理人:

摘要：

The present invention provides, among other things, compositions and methods for CNS delivery of lysosomal enzymes for effective treatment of lysosomal storage diseases. In some embodiments, the present invention includes a stable formulation for direct CNS intrathecal administration comprising an iduronate-2-sulfatase (I2S) protein, salt, and a polysorbate surfactant for the treatment of Hunters Syndrome.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/