Bei Chen,Tao Jiang,Thomas H. Marsilje,Pierre-Yves Michellys,Truc Ngoc Nguyen,Wei Pei,Baogen Wu,Zhaobo Gao,Yonghui Ge,Chen Huang,Yuncheng Li,Xuefeng Zhu
申请号:
US12936199
公开号:
US08592432B2
申请日:
2009.04.03
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention provides novel pyrimidine derivatives and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of anaplastic lymphoma kinase (ALK) activity, c-ros oncogene (ROS), insulin-like growth factor (IGF-1R), and/or insulin receptor (InsR) or a combination thereof.