The utility model provides an egg shell membrane microparticle structure, which sequentially comprises an egg shell membrane core, a chondroitin layer and a collagen layer from the center to the outside, and optionally further comprises a methylthiomethane layer and a turmeric layer. The microparticle structure of the egg shell membrane has the effect of promoting the regeneration of articular cartilage, preventing and alleviating the pain accompanying arthritis, and is convenient to carry and use.本新型提供一種卵殼膜微粒結構,其由中心至外側依序包含一卵殼膜核心、一軟骨素層、以及一膠原蛋白層,並可選擇性地進一步包含一甲基硫醯基甲烷層及一薑黃層。本新型之卵殼膜微粒結構具有促進關節軟骨再生、預防及減輕關節炎伴隨之疼痛的功效,並且方便攜帶與使用。