There is disclosed a system and method for measuring arterial and venous blood pulse waveforms (BPWs) of a subject utilizing photoplethysmography (PPG). In an embodiment, the system and method comprises: providing a plurality of virtual sensors positioned to cover a desired field-of-view of the subject, each virtual sensor adapted to detect and measure a BPW signal from an area of the subject's body and provide a BPW signal output； processing the BPW signal outputs of the plurality of virtual sensors to compare the BPWs at multiple areas of the subject's body to perform spatial perfusion analysis； and displaying at least one aggregate output based on the spatial perfusion analysis. At least one aggregate output may include a visualization of one or more perfusion patterns overlaid on a photographic image of the subject, and aggregate statistics including subject heart rate and breathing rate. The system and method may use a signal from one of the virtual sensors as a reference waveform for cardiovascular monitoring in the generation of parametric maps for assessing BPW characteristics at various parts of the body simultaneously. The system and method may also include a contact photoplethysmography (PPG) sensor, which is connected to the DSP and provides a BPW as a reference waveform for improved cardiovascular monitoring in the generation of parametric maps for assessing BPW characteristics at various parts of the body simultaneously.
