The invention discloses Gynura divaricatas to prepare the application in liver-protecting medicine or health food. For the present invention it has been investigated that acute liver caused by what CCl4, Gynura divaricata alcohol extracting, water raising dosage group have significantly inhibiting effect, show as reducing serum paddy third, glutamic-oxalacetic transaminease, mitigate degeneration of liver cells, necrosis.本發明公開了白子菜在製備護肝藥物或保健食品中的應用。本發明經研究發現對於CCl4所致的小鼠急性肝損傷,白子菜醇提、水提高劑量組有明顯地抑制作用,表現爲降低血清谷丙、谷草轉氨酶,減輕肝細胞變性、壞死。