Bruce M. Spiegelman,Jiandie Lin,Christopher B. Newgard
申请号：
US11577614
公开号：
US08889639B2
申请日:
2005.10.21
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention provides methods for treating lipid-related diseases and disorders, e.g., hyperlipidemia, hypertriglyceridemia, hypercholesterolemia, cardiovascular disease, obesity, and type II diabetes, and for modulating lipid biosynthesis, lipid transport, plasma triglyceride levels and/or plasma cholesterol levels, by modulating the expression or activity of PGC-1β. Methods for identifying compounds which are capable of treating or preventing a lipid-related disease or disorder are also described.
