Bettina STRACK-LOGUE;SHIRE-NPS PHARMACEUTICALS, INC.;Kefeng SUN
发明人:
Clark PAN,Angela NORTON,Bettina STRACK-LOGUE,Kefeng SUN
申请号：
US16640965
公开号：
US20200199192A1
申请日:
2018.08.21
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Described are fusion proteins of GLP-2 with an Fc region of immunoglobulin. The GLP-2 and Fc regions are separated by a linker comprised of amino acids. The fusion proteins persist and remain active in the body for longer periods of time than GLP-2 itself. Methods are disclosed of using the fusion proteins to treat and prevent enterocutaneous fistulae, radiation damage to the gastrointestinal tract, obstructive jaundice, and short bowel syndrome.
