Devices, systems, and methods for treating aneurysms and other medical conditions. A method of the present disclosure includes the steps of introducing a device into a lumen of a mammalian luminal organ at or near an aneurysm, the device comprising an expandable member, and a material layer coupled to the expandable member, wherein the expandable member is configured to attach to an elongated body configured to deliver an inflation material therethrough and into the expandable member, and inflating the expandable member so that the material layer contacts the mammalian luminal organ and adheres to the mammalian luminal organ at or near the aneurysm.
