Systems methods and devices for detecting infections in a clinical sample are provided. Small volume clinical samples obtained at a point of service (POS) location and may be tested at the POS location for multiple markers for multiple diseases including upper and lower respiratory diseases. Samples may be tested for cytokines or for inflammation indicators. Dilution of samples or levels of detection may be determined by the condition or past history of a subject. Test results may be obtained within a short amount of time after sample placement in a testing device or within a short amount of time after being obtained from the subject. A prescription for treatment of a detected disorder may be provided and may be filled at the POS location. A bill may be automatically generated for the testing or for the prescription may be automatically sent to an insurance provider and payment may be automatically obtained.
