WONKWANG UNIVERSITY CENTER FOR INDUSTRY-ACADEMY COOPERATION
发明人:
Ji-Myung Bae,Ju-Lee SON
申请号：
US15550606
公开号：
US20180071180A1
申请日:
2016.05.27
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to a pharmaceutical composition for prevention and treatment of dental caries comprising a fluoride varnish and an antibacterial substance as active ingredients. The fluoride varnish composition comprising xanthorrhizol, bakuchiol, bavachalcone, isobavachromene or bavachromene according to the present invention exhibits significant antibacterial activities against the strain Streptococcus mutans (S. mutans), which causes dental caries. In particular, the composition exhibits remarkable antibacterial activities compared xanthorrhizol, bakuchiol, bavachalcone, isobavachromene, bavachromene or a fluoride varnish. Therefore, the fluoride varnish comprising xanthorrhizol, bakuchiol, bavachalcone, isobavachromene or bavachromene can be usefully used for prevention and treatment of dental caries.
