Boris M. Seletsky,Galina Kuznetsov,Hu Yang,James Kowalczyk,Mark Spyvee,Shawn Schiller
申请号:
BRPI0308606
公开号:
BRPI0308606B1
申请日:
2003.03.21
申请国别(地区):
BR
年份:
2019
代理人:
摘要:
"Hemiasterlin derivatives and uses thereof". The present invention provides compounds having the formula (I): and additionally provides methods for the synthesis thereof, and methods for its use in the treatment of cancer, where r ~ 1 ~ r ~ 7 ~, x ~ 1 ~, x ~ 2 ~, r, q, and n are as defined herein."derivados de hemiasterlina e usos destes". a presente invenção fornece compostos que possuem a fórmula (i): e adicionalmente fornece métodos para síntese deste, e métodos para o uso deste no tratamento de câncer, onde r~ 1~r~ 7~, x~ 1~, x~ 2~, r, q, e n são conforme definido aqui.