A method of cleaning and sterilizing a drink filling apparatus including a CIP process of circulating a cleaner in a drink supply piping to remove foreign matter on an interior of the drink supply piping, and an SIP process of sterilizing the interior of the drink supply piping. The processes are performed at the same time or in sequence without an interruption between the two. The SIP process uses the cleaner to sterilize the interior of the drink supply piping. After the SIP process, while the cleaner is kept circulating, a temperature condition at a predetermined position in the drink supply piping is adjusted to a temperature setting for manufacture, after which the cleaner in the drink supply piping is removed.
