Embodiments of the invention relate to veterinary compositions and methods for the treatment of Equine Protozoal Myeloencephalitis. Specifically, embodiments of the present invention feature methods and compositions designed to treat horses with EPM by killing the protozoan parasites in the horse's body and by providing agents that limit or remedy the damage caused by the protozoan parasites. In particular embodiments, therapeutically effective amounts of Vitamin E Succinate 1185 IU, Levamisole Hydrochloride, Decoquinate, Diclazuril, and Banana powder are administered to the horse for the treatment of Equine Protozoal Myeloencephalitis.
