CHANDRASHEKHAR GARGOTE,LALIT GARG,SHRIKANT VAIJANATHAPPA,SUBODH DESHMUKH,ROMI BARAT SINGH,VIKAS BATRA,SOM AKSHAY JAIN
申请号：
IN201817017117
公开号：
IN201817017117A
申请日:
2018.05.07
申请国别(地区):
IN
年份:
2018
代理人:
摘要：
The present invention relates to pharmaceutical composition comprising dimethyl fumarate an enzyme modulator or a permeation enhancer or both and one or more pharmaceutically acceptable excipients. It further relates to a pulsatile release pharmaceutical composition comprising dimethyl fumarate and one or more pharmaceutically acceptable excipients. The compositions of the present invention are administered at a lower dose as compared to the recommended daily dose of Tecfidera®. Further, the compositions of the present invention are resistant to dose dumping in the presence of alcohol.
