Yong MA;Ming HU;Song GAO;UNIVERSITY OF HOUSTON SYSTEM
发明人:
Ming Hu
申请号：
US15568195
公开号：
US20180098965A1
申请日:
2016.04.20
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Drugs have been designed and developed with a structural motif allowing local bioavailability in the target organ but that are not broadly distributed at a concentration sufficient to illicit toxic side effects in non-targeted organs. The structural motif subjects the compound to be rapidly metabolized by metabolic enzymes before reaching the non-targeted organs.
