Development of HBV-and/or HDV-susceptible cells, cell lines and non-human animals

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专利权人:

RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG

发明人:

Stephan Urban,Yi Ni

申请号：

US14442279

公开号：

US10618947B2

申请日:

2013.11.12

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The present invention relates to a novel Hepatitis B virus (HBV) and/or Hepatitis D virus (HDV) receptor and its use for the development of cells, cell lines and non-human animals that are susceptible to HBV and/or HDV infection and can be used for immunological studies and/or for the screening of drugs, post-entry restriction factors and host dependency factors. It further relates to the use of the receptor for the identification of compounds useful in the treatment of HBV and/or HDV infection.

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