BIGNAN, GILLES C.,BRANCH, JONATHAN,CONNOLLY, PETER J.,TRABALON ESCOLAR, LUIS B.,HICKSON, IAN,MEERPOEL, LIEVEN,PANDE, VINEET,ROCOBOY, CHRISTIAN,ZHANG, ZHUMING
申请号:
CA3030184
公开号:
CA3030184A1
申请日:
2017.07.06
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
Disclosed are compounds, compositions and methods for treating and/or ameliorating diseases, syndromes, disorders, or conditions associated with AR mutant receptors linked to castration-resistant prostate cancer, in a subject, including a mammal and/or human, in need thereof, who has demonstrated resistance to a first or second generation AR antagonist, comprising, consisting of, and/or consisting essentially of, administering to a subject in need thereof, a therapeutically effective amount of a compound falling within the scope of Formula (I).