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INFECTIOUS BRONCHITIS VIRUS VACCINE USING NEWCASTLE DISEASE VIRAL VECTOR
专利权人:
University of Maryland; College Park
发明人:
Siba K. SAMAL,Edris SHIRVANI
申请号:
US16483969
公开号:
US20190358316A1
申请日:
2018.02.06
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Provided are compositions and methods that involve recombinant Newcastle disease viruses (rNDVs) that contain an S protein of infectious bronchitis virus (IBV). The rNDV particles include a contiguous segment of IBV S protein that spans an IBV cleavage site between IBV SI and IBV S2 proteins, and can include a full length IBV S protein. Because the particles are multivalent they also stimulate a protective immune response against NDV infection. The compositions are particularly useful for use with avian animals, such as chickens. Isolated rNDV particles, and vaccine compositions that contain them are also provided.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
相关发明人
edris shirvani
siba k. samal
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