The invention relates to an apparatus (100) for surface treatment of tissue by using dry ice particles (19) comprising a first inlet port (2) for connection to a first source (1) of medical pressurized liquid carbon dioxide and a first agglomeration chamber (4), which is configured for making dry ice snow (5) by delivering pressurized liquid carbon dioxide into said agglomeration chamber (4) and expanding said pressurized liquid carbon dioxide within said agglomeration chamber (4). The first agglomeration chamber (4) is fluid-connectable or fluid-connected to the first inlet port (2). The apparatus (100) further comprises a compressing device (6) being configured for compressing the dry ice snow (5) made in the agglomeration chamber (4) at least partly into compressed dry ice (14), a shredding device (12) being configured for shredding the compressed dry ice (14) at least partly into dry ice particles (19) and an outlet for discharging the dry ice particles (19). The apparatus (100) is configured for making medical, in particular medical clean, dry ice particles (19).
