LAURA SUE GROSMAIRE,MARTHA SUSAN HAYDEN-LEDBETTER,JEFFREY A. LEDBETTER,PETER ARMSTRONG THOMPSON,SANDY ALEXANDER SIMON,WILLIAM BRADY
申请号：
HK11110031.7
公开号：
HK1155761B
申请日:
2008.10.20
申请国别(地区):
HK
年份:
2015
代理人:
摘要：
The present disclosure generally provides methods for B-cell reduction in an individual using CD37-specific binding molecules. In particular, the disclosure provides methods for B-cell reduction using CD37-specific binding molecules alone, or a combination of CD37-specific binding molecules and CD20-specific binding molecules, in some instances a synergistic combination. The application further provides materials and methods for treatment of diseases involving aberrant B-cell activity. In addition, the disclosure provides humanized CD37-specific binding molecules.
