Alexander Scheffold;Sascha Rutz;Frederick Heinrich
发明人:
Alexander Scheffold,Sascha Rutz,Frederick Heinrich
申请号:
US13201638
公开号:
US20120045458A1
申请日:
2010.02.16
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention relates to the use of notch regulators for modulating IL-22 production in T-cells, by influencing the activity or activation of the notch signal path. The invention further relates to the use of modulating the immune response, primarily in case of infection reactions. The invention in particular relates to the use for treating illnesses associated with infections. The invention further relates to the use for reducing IL-22 production in T-cells.