The present invention relates to ophthalmic compositions such as contact lenscare solutions, containing miltefosine. The present invention further relatesto ophthalmic compositions or contact lens care systems containing miltefosinein combination with additional other active microbiocidal substances orproteases. Furthermore, the invention relates to the use of the compositionsfor the removal and eradication of protozoan parasites such as Acanthamoebafrom contact lenses.
