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NON-INVASIVE DIAGNOSTIC BIOMARKER FOR PANCREATIC ISLET POPULATIONS
专利权人:
University of Florida Research Foundation, Incorporated;Johns Hopkins University, The
发明人:
Eric C. Porges,Damon Lamb,Martha Campbell Thompson,Richard Edden
申请号:
US16756489
公开号:
US20200300793A1
申请日:
2018.10.17
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Aspects of the disclosure relate to systems and methods for obtaining and interpreting magnetic resonance spectroscopy (MRS) data obtained from the pancreas of a subject. In some embodiments, systems and methods of the disclosure relate to analyzing MRS spectra of metabolites, for example y-Aminobutyric acid (GABA), to assess pancreatic islet density and function in a subject. In some embodiments, systems and methods described by the disclosure are useful for the diagnosis and/or treatment of diseases associated with impaired pancreatic function, for example diabetes.
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