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Compositions of less immunogenic and long-circulating protein-lipid complexes
专利权人:
The Research Foundation Of State University Of New York
发明人:
Straubinger, Robert M.,Peng, Aaron,Balu-Iyer, Sathy V.,Michlea, Razvan
申请号:
AU2007235463
公开号:
AU2007235463B2
申请日:
2007.03.30
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
Provided are lipidic particles comprising phopatidylcholine, phosphatidylinositol and cholesterol. Also provided are compositions comprising the lipidic particles and having associated therewith therapeutic agents such as peptides, polypeptides or proteins. In these compositions, the therapeutic agents have reduced immunogenicity and/or longer circulating time. These compositions can be used for therapeutic administration of the peptides, polypeptides and/or proteins.
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