Shantha Arcot-Krishnamurthy;Bruce H. KenKnight;Douglas R. Daum;Allan C. Shuros
发明人:
Allan C. Shuros,Shantha Arcot-Krishnamurthy,Bruce H. KenKnight,Douglas R. Daum
申请号：
US12397464
公开号：
US08626288B2
申请日:
2009.03.04
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Various embodiments intermittently deliver a sympathetic stimulus, including deliver a sequence of stress-inducing pacing pulses adapted to increase sympathetic tone during the stress-inducing pacing. The stress-inducing pacing results in a parasympathetic reflex after the sequence of stress-inducing pacing. The embodiment further delivers neural stimulation to elicit a parasympathetic response or a sympathetic response in a coordinated manner with respect to the sequence of stress-inducing pacing pulses. The neural stimulation is timed to elicit the parasympathetic response after the sequence of stress-inducing pacing pulses and concurrent with at least a portion of the parasympathetic reflex to the sequence of stress-inducing pacing to enhance a parasympathetic effect of the parasympathetic reflex, or to elicit the sympathetic response during the sequence of stress-inducing pulses to provide a larger sympathetic stimulus, resulting in an enhanced parasympathetic reflex in response to the large sympathetic stimulus.
