GLAXOSMITHKLINE INTELLECTUAL PROPERTY (No.2) LIMITED;ANACOR PHARMACEUTICALS, INC.
发明人:
ALEMPARTE-GALLARDO, Carlos,ALLEY, M. R. K. (dickon),BARROS-AGUIRRE, David,GIORDANO, Ilaria,HERNANDEZ, Vincent,LI, Xianfeng,PLATTNER, Jacob J.
申请号：
PE2017001401
公开号：
PE20171348A1
申请日:
2016.02.12
申请国别(地区):
PE
年份:
2017
代理人:
摘要：
It refers to the boron benzoate derivatives with type III formula: R1 and R2 are h, CH3, CH2 are CH3, CH3 (CH3) 2； R3 is CH3, CH2 is CH3, CH2 is CH2, CH2 is ch2ch3, CH3 is CH3 (CH3) 2, CH2CH2 is CH2, cyclopile. It also refers to compounds containing these compounds. The most popular compounds are: 3-methyl-7,8-dihydro-2h-1,6,9-trinitro-9a-boranzo - [CD] - s-2-il-methylamine； 3,8-dimethyl-7,8-dihydro-2h-1,6,9-trinitro-9a-boranzo - [CD] - s-2-il-methylamine； and other compounds. These compounds are used to treat bacterial infections such as tuberculosis.Se refiere a derivados de benzoxaborol sustituidos de Formula III, en donde: R1 y R2 son H, CH3, CH2CH3, CH2CH2CH3, CH(CH3)2； y R3 es CH3, CH2CH3, CH2=CH2, CH2CH2CH3, CH(CH3)2, CH2CH2=CH2, ciclopropilo. Tambien se refiere a composiciones que contienen estos compuestos. Entre los compuestos preferidos tenemos los siguientes: 3-metil-7,8-dihidro-2H-1,6,9-trioxa-9a-borabenzo-[cd]-azulen-2-il)-metanamina； 3,8-dimetil-7,8-dihidro-2H-1,6,9-trioxa-9a-borabenzo-[cd]-azulen-2-il)-metanamina； entre otros. Estos compuestos se emplean en el tratamiento de infecciones micobacterianas como por ejemplo la tuberculosis.
